Synthetic community of the yeast for bioproduction by Young-Kyoung PARK

Synthetic community of the yeast for bioproduction by Young-Kyoung PARK

Abstract: Microorganisms can be engineered to sustainably produce a variety of products, including fuels, pharmaceuticals, materials, and food. However, highly engineered strains often result in low production yield, due to undesired effects such as metabolic burden and the toxicity of intermediates. Drawing inspiration from natural ecosystems, the construction of a synthetic community with division of labor can offer advantages for bioproduction. This approach involves dividing specific tasks among community members, thereby enhancing the functionality of each member. In this presentation, I will present the identification and characterization of synthetic syntrophic communities by yeasts (Saccharomyces cerevisiae, Yarrowia lipolytica). The effect of division of labor using the syntrophic community on bioproduction will be also presented. 

Biography: I've been working on developing microbial cell factories for bioproduction by using metabolic engineering and synthetic biology. By engineering a non-conventional yeast, Yarrowia lipolytica, we have shown a variety of products from this yeast. Now we are establishing a synthetic community with this yeast to improve its functionality and decrease metabolic burden. I'm working at Micalis institute (INRAe, France), in the team 'Cosynus'. Cosynus is working on implementing synthetic biology tools and strategies to transform Yarrowia lipolytica into an industrial cell factory producing value-added molecules like pigments and terpenes.

More information about Young-Kyoung: https://www.micalis.fr/membre/young-kyoung-park/